PRP Platelet Concentration Calculator – Instructions

This calculator helps estimate the platelet concentration in your PRP (Platelet-Rich Plasma) sample based on the volume of blood drawn, the final PRP volume, and your patient’s baseline platelet count.

How to Use the Calculator:

1. Volume of Blood Drawn (ml):
   Enter the total amount of blood collected for PRP processing (e.g., 54 mL).

2. Volume of PRP Created (ml):
   Enter the final volume of PRP after centrifugation (e.g., 7 mL).

3. Recovery Rate (default 0.9 for 90%):
   This represents the efficiency of platelet recovery during processing.

   • The default value is 0.9 (90%), based on peer-reviewed studies showing that EmCyte PRP kits recover, on average, 90% of platelets (Marx, 2004; Mazzocca et al., 2012).

   • If using a different system, adjust this value based on manufacturer data or lab validation.

4. Baseline Platelet Count (per µL):
   Enter the patient’s platelet count before PRP processing.

   • The default is 250,000/µL (average healthy adult).

   • For accurate results, input the patient’s actual lab value if available.

5. Click “Calculate”:
   The tool will compute:

   • Total Platelets in PRP (absolute count)

   • Platelet Concentration in PRP (per µL)

   • Concentration Factor (how many times more concentrated than baseline)

Scientific Reference for 90% Recovery Rate:

The default 90% recovery rate is based on studies of EmCyte PRP systems, which demonstrate high platelet capture efficiency:

• Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent. 2004;10(4):225-228.

• Mazzocca AD, et al. Platelet-rich plasma differs according to preparation method and human variability. J Bone Joint Surg Am. 2012;94(4):308-316.

For other PRP kits, consult manufacturer data or clinical studies for appropriate recovery rates.

Why This Matters:

• Higher concentration factors (typically 3–8× baseline) are associated with improved clinical outcomes in orthopedic and regenerative applications.

• Total platelet count helps ensure sufficient bioactive factors (e.g., growth factors) are delivered to the target tissue.

Use this calculator to standardize PRP preparation and optimize therapeutic dosing.