Emcyte PRP Kits vs Apex PRP Kits

In recent years, Platelet-Rich Plasma (PRP) therapy has emerged as a cornerstone of regenerative medicine, gaining widespread adoption across both aesthetic and orthopedic fields. By harnessing the body’s natural healing mechanisms, PRP offers a minimally invasive option for patients seeking relief from joint pain, soft tissue injuries, and skin aging.

As clinical interest has grown, so too has the range of PRP systems available on the market—each designed to isolate and concentrate platelets with varying levels of efficiency, purity, and customization. Choosing the right PRP system is critical, as it directly impacts treatment efficacy, patient outcomes, and practice workflow.


Choosing the right platelet-rich plasma (PRP) system is critical to patient outcomes, procedural consistency, and practice success. Whether you’re treating musculoskeletal injuries, offering aesthetic services, or expanding into regenerative medicine, not all PRP systems deliver the same results.

Below is a head-to-head comparison of two FDA-cleared PRP systems: EmCyte PurePRP® SupraPhysiologic (SP) and Apex XCELL PRP.

🔬 PRP System Comparison Table

FeatureEmCyte PurePRP® SPApex XCELL PRP
FDA ClearanceBK190317BK180252
Platelet Recovery~90%~71%
Platelet Concentration Factor4-32x baseline (7–24 billion platelets)3–9x baseline (>7.5 billion platelets)
Leukocyte ControlProtocol A (leukocyte-poor) & Protocol B (leukocyte-rich)LL-PRP and LE-PRP options, limited flexibility
System TypeClosed, dual-spin systemOpen, single-spin with benchtop processor
Contamination RiskMinimized via sterile, sealed setupIncreased due to open handling
CustomizabilityHigh—flexible platelet yield and leukocyte configurationLimited
Ease of IntegrationStreamlined workflow; minimal learning curveRequires setup with an external processor
Peer-Reviewed ValidationMultiple studies show >90% recovery and consistent outputNo known peer review validation
Best Suited ForOrthopedics, aesthetics, sports medicine, high-performance clinicsEntry-level or general use PRP clinics
Authorized Distributor SupportAvailable through PRP Labs with full training, marketing & clinical resourcesVendor-dependent

Why EmCyte Stands Apart

EmCyte’s PurePRP® SP is one of the most clinically validated PRP systems available today. It is widely used in both aesthetic and orthopedic practices that demand high platelet concentration, customization, and FDA-cleared safety in a seamless, closed-system format.

Unlike systems that require external devices or compromise on purity, EmCyte delivers consistent performance from blood draw to injection—minimizing contamination risk while offering clinician-controlled output.

Peer-Reviewed Proof of Performance

A 2020 study by Merrell et al. published in Current Orthopaedic Practice compared PRP systems head-to-head. EmCyte PurePRP® SP achieved over 90% platelet recovery with customizable leukocyte content and minimal RBC contamination—demonstrating a higher therapeutic payload than competing systems.

Reference:
Merrell GA, Karukonda T, Ahmed M, Jaskulka RA, Schaefer D. A head-to-head comparison of blood separation systems for platelet-rich plasma in musculoskeletal injections. Curr Orthop Pract. 2020;31(2):174–178. PubMed

About Apex XCELL PRP

The Apex XCELL PRP system offers a single-spin design with modest platelet concentration (average ~71% recovery). While marketed as user-friendly, it requires a proprietary benchtop station for processing, introducing more setup time and complexity than fully integrated closed systems like EmCyte.

Additionally, there is no known peer-reviewed clinical evidence supporting Apex’s real-world performance. Clinics using the system should weigh the tradeoff between simplicity and performance when treating patients with higher therapeutic demands.

FDA Clearance and Safety

Both systems are FDA-cleared for autologous PRP preparation at the point of care:

  • EmCyte PurePRP® SP: 510(k) Clearance BK190317

  • Apex XCELL PRP: 510(k) Clearance BK180252

FDA clearance confirms that each system meets the baseline safety and manufacturing standards. However, FDA clearance does not imply equal clinical performance—that depends on design, yield, and clinical outcomes, where EmCyte clearly leads.

Understanding PRP: Mechanism and Clinical Applications

Platelet-Rich Plasma (PRP) therapy is a regenerative treatment that utilizes the body’s natural healing processes. By concentrating platelets from a patient’s own blood, PRP delivers a high concentration of growth factors and cytokines to targeted areas, promoting tissue repair and regeneration.

Mechanism of Action

Platelets play a crucial role in healing by releasing bioactive proteins that stimulate cellular processes essential for tissue repair. Key growth factors released include:

  • Platelet-Derived Growth Factor (PDGF): Stimulates cell replication and angiogenesis.

  • Transforming Growth Factor-beta (TGF-β): Regulates inflammation and promotes matrix synthesis.

  • Vascular Endothelial Growth Factor (VEGF): Enhances blood vessel formation.

  • Epidermal Growth Factor (EGF): Promotes cell growth and differentiation.

These factors collectively accelerate the healing process by attracting reparative cells, enhancing collagen production, and improving blood flow to the injured area .

Clinical Applications

PRP therapy has been applied across various medical fields due to its regenerative properties:

  • Musculoskeletal Injuries: Effective in treating conditions like tennis elbow, Achilles tendinopathy, and rotator cuff tears .

  • Osteoarthritis: Intra-articular PRP injections have shown promise in reducing pain and improving function in knee osteoarthritis patients .

  • Aesthetic Medicine: Used for skin rejuvenation, reducing wrinkles, and improving skin texture .

  • Hair Restoration: PRP injections can stimulate hair growth in individuals with androgenetic alopecia 

The versatility of PRP therapy lies in its ability to harness the body’s innate healing mechanisms, making it a valuable tool in both clinical and aesthetic settings.

Which PRP System Aligns With Clinical Outcomes?

When choosing a PRP system, clinicians should prioritize platelet recovery, concentration, and biological purity, as these factors directly influence the treatment’s therapeutic potential.

Multiple peer-reviewed studies suggest that higher concentrations of platelets can improve treatment outcomes in orthopedic and aesthetic medicine:

“The clinical efficacy of PRP is dose-dependent, with better outcomes seen when higher platelet concentrations are delivered.”
Dhurat R, Sukesh MS. Principles and methods of preparation of platelet-rich plasma: A review and author’s perspective. J Cutan Aesthet Surg. 2014. PubMed

“A higher platelet concentration in PRP correlates positively with anabolic effects on cartilage and pain relief in osteoarthritis.”
Patel S, Dhillon MS, Aggarwal S, Marwaha N, Jain A. PRP is more effective than placebo for knee OA. Arthritis Res Ther. 2013. BioMed Central

With this evidence in mind:

✅ Choose EmCyte PurePRP® SP if your practice:

  • Requires high platelet recovery (~90%) and concentration ( up to 32x baseline)

  • Treats advanced orthopedic, sports medicine, or aesthetic patients

  • Benefits from flexible leukocyte control (via Protocol A and B)

  • Prefers a closed, sterile system with simplified training and setup

  • Wants to align with peer-reviewed clinical data supporting therapeutic outcomes

Work With a National EmCyte Distributor

PRP Labs is the authorized national distributor for EmCyte. We go beyond simply supplying kits—we provide:

  • Clinical onboarding & Zoom training

  • Ongoing support from real PRP specialists

  • Marketing assets to help you attract patients

  • Exclusive pricing and subscription options

🎯 Ready to bring EmCyte into your practice?
Click here to schedule a demo or request pricing

References

  • Merrell GA, Karukonda T, Ahmed M, Jaskulka RA, Schaefer D. A head-to-head comparison of blood separation systems for platelet-rich plasma in musculoskeletal injections. Curr Orthop Pract. 2020;31(2):174–178. PubMed

  • Prysak M, et al. A Retrospective Analysis of a Commercially Available Platelet-Rich Plasma Kit During Clinical Use. Curr Orthop Pract. 2021;32(1):50–56. PubMed

  • Patel S, Dhillon MS, Aggarwal S, Marwaha N, Jain A. Treatment With Platelet-Rich Plasma Is More Effective Than Placebo for Knee Osteoarthritis: A Prospective, Double-Blind, Randomized Trial. Arthritis Research & Therapy. 2013;15(1):R122. BioMed Central

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Picture of Daniel Zengel
Daniel Zengel

Daniel Zengel, an executive with over 10 years of experience in the pharmaceutical and medical device space, is dedicated to delivering industry-leading, cost-effective products to US-based medical providers. Specializing in regenerative medicine, Daniel focuses on sales, training, and marketing support to help clinics across the country successfully implement platelet-rich plasma (PRP) therapy.

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