The authors claimed the PRP injections stimulated ovarian rejuvenation, but are these claims well-founded? The menopausal transition is long and complex. Can we attribute folliculogenesis to the PRP injection or is sporadic ovulation normal in this population? To begin to answer these questions, let’s review what we understand about the menopause transition.⁴
Since 1996, Samar R. El Khoudary, PhD, MPH, FAHA, Associate Professor of Epidemiology at the University of Pittsburgh has been conducting a large and diverse, longitudinal Study of Women’s Health Across the Nation (SWAN). Over the past 23 years the study has tracked 3,302 women, documenting changes in mental health and physiological systems over the menopause transition. The data shows that natural menopause (defined as the lack of menstruation for 12 consecutive months) occurs just beyond the age of 50 for most women. Menstrual cycles begin to lengthen and the rate of ovulatory cycles slowly decrease an average of 7.5 years before the final period.